Mediator and human disease
نویسندگان
چکیده
منابع مشابه
Oxidative Stress and Human Disease: a Review
Background: The human body needs both types of oxidants (free radicals) and antioxidants for normal metabolism, signal transduction mechanism, and the order of cellular activity. Free radicals can be either harmful or helpful to the body, in fact, they play a dual role as both toxic and beneficial compounds. The human body has the natural antioxidant defense mechanism to counteract the free rad...
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The term “medicinal” as applied to a plant indicates that it contains a substance or substances which modulate beneficially the physiology of sick mammals. Thousands of species of higher plants have been used by man for that purpose. Modern techniques have revealed the enormous variety and complexity of so-called secondary plant chemicals, i.e., those which do not occur in all species, but whic...
متن کاملEvidence-based bioactive phytoconstituents for human health and disease prevention
The term “medicinal” as applied to a plant indicates that it contains a substance or substances which modulate beneficially the physiology of sick mammals. Thousands of species of higher plants have been used by man for that purpose. Modern techniques have revealed the enormous variety and complexity of so-called secondary plant chemicals, i.e., those which do not occur in all species, but whic...
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Of the various hypotheses offered to explain atherosclerosis, inflammation now appears to provide a key to this pathological process. Inflammation has been shown to play a major role in precipitating a cascade of events from formation of the atheromatous lesion in response to vascular injury through lipid ingestion by macrophages, to subsequent rupture of the lesion, and myocardial infarction. ...
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A symmetric dimethylarginine (ADMA) is a naturally occurring amino acid that circulates in blood and is excreted in urine (1). It is also a competitive inhibitor of all three isoforms of nitric oxide synthase (NOS). ADMA competes with arginine for the binding site of NOS with an IC50 of about 10 M depending on the prevailing concentration of arginine (2). Combine these observations and it is po...
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ژورنال
عنوان ژورنال: Seminars in Cell & Developmental Biology
سال: 2011
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2011.07.024